त्रिविधमेव कर्म प्रज्ञापराध इति व्यवस्येत् ।
trividham eva karma prajñāparādha iti vyavasyet |
(Caraka-saṁhita: 1.11.41)
“Action (karma) of these three types [i.e., overuse, disuse, or misuse of the mind, speech, and body as categorized in two prior passages] should be regarded as prajñāparādha [i.e., a transgression of discernment].”